Mona Ameri Chalmer

Hovedpinespecialist, Læge (PhD) hos Hemi
Mona Ameri Chalmer

Ekspertiseområder

Behandling af migræne, menstruationsrelateret migræne (hormonel migræne) og hovedpine.

Personlig tilgang til behandling

Jeg gør mig umage for at forstå den enkelte person og dennes problemstillinger og vil altid forsøge at gøre mit bedste for at finde det rette, individualiserede behandlingstilbud mod hovedpine.

Uddannelse

2016 - 2020: Ph.D, Københavns Universitet, Dansk Hovedpinecenter

2009 - 2016: Lægeuddannelsen, Københavns Universitet

Erfaring

2025-: Hovedpinespecialist og læge, Hemi Hovedpineklinik

2025-: Speciallægeuddannelse i neurologi

2024 - 2025: Introduktionsstilling i neurologi

2023 - 2024: KBU

2020 - : Postdoc, Dansk Hovedpinecenter

2016 - 2020: Ph.D., Dansk Hovedpinecenter

2014 - 2015: Fuldtidsansat som medicinstuderende tilknyttet forskning i migræne, Dansk Hovedpinecenter

Forskningsinteresser

Involveret i migræneforskning siden 2014. Primært inden for migrænegenetik og menstruationsrelateret migræne.

Første (*delt-første) og sidste forfatterskaber:

1. Bjornsdottir G*, Chalmer MA*, et al. Rare variants with large effects provide functional insights into the pathology of migraine subtypes, with and without aura. Nat Genet. 2023 Nov;55(11):1843-1853.
https://doi.org/10.1038/s41588-023-01538-0

2. Winsvold BS*, Harder AVE*, Ran C*, Chalmer MA*, et al.Cluster Headache Genomewide Association Study and Meta-Analysis Identifies Eight Loci and Implicates Smoking as Causal Risk Factor. Ann Neurol. 2023 Oct;94(4):713-726.
https://doi.org/10.1002/ana.26743

3. Chalmer MA and Lønberg US. Health-Care Seeking Behavior and Treatment of Menstrual Migraine among Danish Women—A Social Media Study. Women [Internet]. 2023 Jul 17;3(3):385–95. Available from:
https://doi.org/10.3390/women3030029

4. Chalmer MA, Kogelman LJA, Callesen I et al. Sex differences in clinical characteristics of migraine and its burden: a population-based study. Eur J Neurol. 2023 Jun;30(6):1774-1784.
https://doi.org/10.1111/ene.15778

5. Chalmer MA, Kogelman LJA, Ullum H. et al. Population-Based Characterization of Menstrual Migraine and Proposed Diagnostic Criteria. JAMA Netw Open. 2023 May 1;6(5):e2313235.
https://doi.org/10.1001/jamanetworkopen.2023.13235

6. Chalmer MA, Rasmussen AH; International Headache Genetics Consortium; 23andme Research Team; Kogelman LJA, Olesen J, Hansen TF. Chronic migraine: Genetics or environment? Eur J Neurol. 2021 May;28(5):1726-1736.
https://doi.org/10.1111/ene.14724

7. Christensen CG, Techlo TR, Kogelman LJ, Wegner Thørner L, Nissen J, Sørensen E, Olesen J, Hansen T, Chalmer MA. Population-based prevalence of cranial autonomic symptoms in migraine and proposed diagnostic appendix criteria. Cephalalgia. 2022 Oct;42(11-12):1160-1171.
https://doi.org/10.1177/03331024221094548

8. Olesen A, Schytz HW, Ostrowski SR, Topholm M, Nielsen K, Erikstrup C, Mikkelsen S, Pedersen OB, Olesen J, Hansen TF, Chalmer MA. Low adherence to the guideline for the acute treatment of migraine. Sci Rep. 2022 May 19;12(1):8487.
https://doi.org/10.1038/s41598-022-12545-2

9. Chalmer MA, Olesen J. Letter to the editor regarding proposed new diagnostic criteria for migraine. Cephalalgia. 2020 Apr;40(4):415-418.
https://doi.org/10.1177/0333102420911190

10. Chalmer MA, Hansen TF, Lebedeva ER, et al. Proposed new diagnostic criteria for chronic migraine. Cephalalgia. 2020 Apr;40(4):399-406.
https://doi.org/10.1177/0333102419877171

11. Ravn J*, Chalmer MA*, et al. Characterization of Familial and Sporadic Migraine. Headache. 2019Nov;59(10):1802-1807.
https://doi.org/10.1111/head.13640

12. Chalmer MA, Hansen TF, Olesen J. Nosographic analysis of osmophobia and field testing of diagnostic criteria including osmophobia. Cephalalgia. 2019 Jan;39(1):38-43.
https://doi.org/10.1177/0333102418771375

13. Chalmer MA, Esserlind AL, Olesen J, Hansen TF. Polygenic risk score: use in migraine research. J Headache Pain. 2018 Apr 5;19(1):29.
https://doi.org/10.1186/s10194-018-0856-0

Medforfatterskaber:

1. Olofsson IA…Chalmer MA, Olesen J, Kogelman LJA, Hansen TF. Genome-wide association study reveals a locus in ADARB2 for complete freedom from headache in Danish Blood Donors. Commun Biol. 2024 May 27;7(1):646.
https://doi.org/10.1038/s42003-024-06299-y (author position in Danish Blood Donor Study Genomic Consortium)

2. Skuladottir AT et al. GWAS meta-analysis reveals key risk loci in essential tremor pathogenesis. Commun Biol. 2024 Apr 26;7(1):504.
https://doi.org/10.1038/s42003-024-06207-4 (author position in Danish Blood Donor Study Genomic Consortium)

3. Qu K, Li MX, Yu P, et al. HMG-CoA reductase is a potential therapeutic target for migraine: a mendelian randomization study. Sci Rep. 2024 May 27;14(1):12094.
https://doi.org/10.1038/s41598-024-61628-9
(author position in International Headache Genetics Consortium)

4. Li G, Duan S; et al. Genetic causal relationship between immune diseases and migraine: a Mendelian randomization study. Front Immunol. 2024 Apr 8;15:1376698.
https://doi.org/10.3389/fimmu.2024.1376698
(author position in International Headache Genetics Consortium)

5. Davidsson OB, Rostgaard K, Chalmer MA, et al. Blood donation and migraine relief: A national population cohort study in Denmark. Transfusion. 2024 Apr;64(4):647-655.
https://doi.org/10.1111/trf.17770

6. Thorolfsdottir RB, Jonsdottir AB, et al. Variants at the Interleukin 1 Gene Locus and Pericarditis. JAMA Cardiol. 2024 Feb 1;9(2):165-172.
https://doi.og/10.1001/jamacardio.2023.4820 (author position in Danish Blood Donor Study Genomic Consortium)

7. Sequeros CB et al. A genome-wide association study of social trust in 33,882 Danish blood donors. Sci Rep. 2024 Jan 16;14(1):1402.
https://doi.org/10.1038/s41598-024-51636-0 (author position in Danish Blood Donor Study Genomic Consortium)

8. Zhang W, Zhang L, et al. Migraine, chronic kidney disease and kidney function: observational and genetic analyses. Hum Genet. 2023 Aug;142(8):1185-1200.
https://doi.org/10.1007/s00439-023-02575-9 (author position in International Headache Genetics Consortium)

9. He Q, Wang W, et al. A causal effects of gut microbiota in the development of migraine. J Headache Pain. 2023 Jul 17;24(1):90.
https://doi.org/10.1186/s10194-023-01609-x (author position in International Headache Genetics Consortium)

10. Sigurdsson AI et al. Deep integrative models for large-scale human genomics. Nucleic Acids Res. 2023 Jul 7;51(12):e67.
https://doi.org/10.1093/nar/gkad373 (author position in Danish Blood Donor Study Genomic Consortium)

11. Banasik K, Møller PL, et al. DanMAC5: a browser of aggregated sequence variants from 8,671 whole genome sequenced Danish individuals. BMC Genom Data. 2023 May 27;24(1):30.
https://doi.org/10.1186/s12863-023-01132-7

12. Petersen AS, Barloese M, Lund N, Pedersen AF, Søborg MK, Chalmer MA et al. Cluster headache polygenetic risk and known functional variants of CYP3A4 are not associated with treatment response. Eur J Neurol. 2023 May;30(5):1425-1434.
https://doi.org/10.1111/ene.15736

13. Zhao L, Zhao W et al. Causal relationships between migraine and microstructural white matter: a Mendelian randomization study. J Headache Pain. 2023 Feb 16;24(1):10.
https://doi.org/10.1186/s10194-023-01550-z
(author position in International Headache Genetics Consortium)

14. Davidsson OB, Rostgaard K, Hjalgrim LL, Chalmer MA, et al. Childhood cancer confers increased risk of migraine - A Danish nationwide register study. Cancer Epidemiol. 2022 Dec;81:102278.
https://doi.org/10.1016/j.canep.2022.102278

15. Hautakangas H, Winsvold BS, Ruotsalainen SE, et al. Genome-wide analysis of 102,084 migraine cases identifies 123 risk loci and subtype-specific risk alleles. Nat Genet. 2022 Feb;54(2):152-160.
https://doi.org/10.1038/s41588-021-00990-0

16. Olofsson IA, Hvedstrup J, Falkenberg K, Chalmer MA., et al. Pain sensitivity in men who have never experienced a headache: an observer blinded case control study. J Headache Pain. 2021 Nov 8;22(1):134.
https://doi.org/10.1186/s10194-021-01345-0

17. Rasmussen AH, Kogelman LJA, Kristensen DM, Chalmer MA., et al. Functional gene networks reveal distinct mechanisms segregating in migraine families. Brain. 2020 Oct 1;143(10):2945-2956.
https://doi.org/10.1093/brain/awaa242

18. Rasmussen AH, Olofsson I, Chalmer MA, et al. Higher burden of rare frameshift indels in genes related to synaptic transmission separate familial hemiplegic migraine from common types of migraine. J Med Genet. 2020 Sep;57(9):610-616.
https://doi.org/10.1136/jmedgenet-2019-106640

19. Techlo TR, Rasmussen AH, Møller PL. et al. Familial analysis reveals rare risk variants for migraine in regulatory regions. Neurogenetics. 2020 Jul;21(3):149-157.
https://doi.org/10.1007/s10048-020-00606-5

20. Yamani N, Chalmer MA, Olesen J. Migraine with brainstem aura: defining the core syndrome. Brain. 2019 Dec 1;142(12):3868-3875.
https://doi.org/10.1093/brain/awz338

21. Hansen TF, Chalmer MA, Haspang TM, et al. Predicting treatment response using pharmacy register in migraine. J Headache Pain. 2019 Apr 2;20(1):31.
https://doi.org/10.1186/s10194-019-0987-y